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:: Volume 7, Issue 3 And 4 (2-2011) ::
Mod Care J 2011, 7(3 And 4): 22-27 Back to browse issues page
Drug interactions frequency in the bedridden patients in three hospitals of Tehran city
A.M Alizadeh , A Rostamian , Kh Saeedpour , M Hemmati , Z Khorasani , M.A Mohagheghi , M Khatami Moghaddam , M Mousavi3
PhD of Physiology Tehran University of Medical Sciences , aalizadeh@razi.tums.ac.ir
Abstract:   (10940 Views)

  Background and Aim: Drug interaction includes the effect of a drug, food or anything that can induce changes in the pharmacokinetic or pharmacodynamic properties of a certain drug. The aim of the present study is to assess drug interactions of bedridden patients in three Tehran hospitals.

  Materials and Methods: This retrospective research was accomplished on 400 bedridden patient’s dossiers in three hospitals of Tehran city at secondary half of 2006 year . Questionnaire was used according to Hansten classifications to gather information from available data.

  Results: Dossiers assessment showed 1087 visits and 2610 drug order. 168 dossiers (42%) were found having drug-drug interactions (568 cases). Drug interactions were severe (4.4%), moderate (47%) and mild (48.6%). Antibiotics had the commonest (27.5%), while the neuroleptics and digitalis (0.5%) and bronchodilators (0.3%) brought about the least drug interactions.

  Conclusion: Our findings showed that the drug prescription doesn't follow a correct logic and is still increasing in comparison to the past.

Keywords: Drug interaction, bedridden patients, Dossier
Full-Text [PDF 138 kb]   (1501 Downloads)    
Type of Study: Systematic Review |
Received: 2012/09/24 | Accepted: 2012/10/9
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Alizadeh A, Rostamian A, Saeedpour K, Hemmati M, Khorasani Z, Mohagheghi M, et al . Drug interactions frequency in the bedridden patients in three hospitals of Tehran city. Mod Care J. 2011; 7 (3 and 4) :22-27
URL: http://moderncare.bums.ac.ir/article-1-81-en.html


Volume 7, Issue 3 And 4 (2-2011) Back to browse issues page
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