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:: Volume 5, Issue 1 (1-2009) ::
Mod Care J 2009, 5(1): 52-56 Back to browse issues page
Assessment of keratometry changes and Refractive Errors in patients with Pterygium before and after injection of mitomycin C
M.H Davari , Sh Pejmankhah , N Abdolah Challaki
, Instructor Birjand University of Medical Sciences, Birjand, Iran , vojodhasti@yahoo.com
Abstract:   (6754 Views)

  Pterygium is the development of pinguecula that makes a mass of oval and palmy shape near limbus and its main treatment is surgery but due to some complications and high recurrence after syrgery, subconjunctival injection of mitomycin -C as a safe and effective treatment was detected in many researches so this study determine this purpose and prevelance in Birjand.

  Materials and Methods: 30 eyes patients with pterygium referred to Vali- Asr of Birjand Hospital received 0.1 ml of 0.2 mg/ml mitomycin -subconjunectively injected into the body of the pterygium. After injection, patients were followed up at first week 3-5 months after pterygium injection. Patients were examimed at all visits for conjunctiva erythematic, epithehial defects and pterygium size reductive (regression of pterygium ). Data were gathered via 3 questionnaires. Then they were analyzed by SPSS and paired T test.(α=0.05)

  Results: The complications after sub. Conjuntive mitomycin- C injection were mild chemosis and lonf discomfort and redness in the site of injection for four days that were seen in six patients (20%). No toxicity of mitomycin- C were found the size of pterygium was reduced in ( mean 0.48 mm ) 83% of cases and in all cases there were not seen progression and the amount of Astigmatism reduced (mean 0.46 diopter) in 70% cases.

  Conclusion: Subconjunctival injection of mitomycin- C is an effective treatment and reduces the size of pterygium as well as redness and astigmatism.

 

Keywords: Pterygium, Mitomycin C, Subconjunctival
Full-Text [PDF 268 kb]   (695 Downloads)    
Type of Study: سایر |
Received: 2012/11/29 | Accepted: 2012/12/12
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Davari M, Pejmankhah S, Abdolah Challaki N. Assessment of keratometry changes and Refractive Errors in patients with Pterygium before and after injection of mitomycin C. Mod Care J. 2009; 5 (1) :52-56
URL: http://moderncare.bums.ac.ir/article-1-189-en.html


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